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  • Christophe Fien


The brain and gut may seem like two very distinct organs, but they are actually closely linked and work together in ways that are still being understood. The connection between these two complex systems is known as the brain-gut connection, and it is a critical aspect of human health and well-being. Essentially, the brain-gut connection refers to the bidirectional communication pathway between the brain and the digestive system. This connection allows the brain to receive information about the state of the gut and vice versa. This communication is essential for regulating digestion, metabolism, and even mood. In this post, we will delve deeper into the brain-gut connection, examining why it matters for our health and how it can be nurtured for optimal functioning.

The Science behind the Connection

The science behind the brain-gut connection is complex and multifaceted, but there is a growing body of research that supports its existence and importance. Scientists have found that the gut is home to a vast network of neurons and neurotransmitters known as the enteric nervous system (ENS), which is sometimes referred to as the "second brain." This system is capable of operating independently of the central nervous system (CNS), but it is also connected to the brain via the vagus nerve. This connection allows the ENS to send signals to the brain and receive signals from it, creating a two-way communication pathway that is essential for regulating digestion, metabolism, and other bodily functions.

Studies have also found that gut microbes play a crucial role in the brain-gut connection. The gut microbiome is a complex community of bacteria, viruses, and other micro-organisms that live in the digestive system. These microbes help to break down food, produce essential vitamins, and support the immune system. They also produce neurotransmitters that can influence mood and behaviour, such as serotonin and dopamine.

Research has shown that disruptions to the gut microbiome can have a significant impact on mental health and cognitive function. For example, studies have found that people with depression and anxiety have different gut microbiome profiles than healthy individuals. Other studies have found that altering the gut microbiome through probiotics or other interventions can improve mood and cognitive function.

How the Brain Affects the Gut

While the gut is often referred to as the "second brain," the brain itself can also have a profound impact on gut health and digestion. When the brain experiences stress or anxiety, it can trigger a cascade of physiological changes that affect the gut. For example, the release of stress hormones like cortisol and adrenaline can cause the muscles in the digestive system to tense up, slowing down digestion and leading to issues like constipation, bloating, and abdominal discomfort.

In addition, stress and anxiety can also disrupt the balance of gut microbes, leading to dysbiosis, inflammation, and other issues. Studies have found that people with high levels of stress or anxiety are more likely to have gut microbiome imbalances and digestive problems.

Other mental health factors, such as depression and trauma, can also impact gut health. For example, research has shown that people with a history of childhood trauma are more likely to develop irritable bowel syndrome (IBS) and other gut-related disorders.

Overall, the brain's impact on gut health and digestion is complex and multifaceted, but it highlights the importance of addressing both mental and physical health when addressing gut-related issues. By managing stress, anxiety, and other mental health factors, individuals may be able to improve their gut health and overall well-being.

How the Gut Affects the Brain

The gut microbiome, a complex community of micro-organisms that live in the digestive system, has been increasingly recognized for its important role in mental health and cognitive function. Studies have found that gut microbes produce neurotransmitters such as serotonin and dopamine, which are involved in mood regulation and can influence anxiety and depression.

Research has also shown that gut microbes can communicate with the brain via the vagus nerve and other pathways, influencing cognitive function and behaviour. For example, studies in mice have found that altering the gut microbiome can impact learning and memory. In humans, research has linked imbalances in the gut microbiome to conditions such as Alzheimer's disease and Parkinson's disease.

In addition, the gut microbiome plays a crucial role in inflammation and immune function, which can have implications for mental health. Chronic inflammation has been linked to depression and other mood disorders, and the gut microbiome is thought to be involved in regulating immune function and inflammation.

Overall, the gut microbiome has a complex and multi-faceted role in mental health and cognitive function. The communication pathway between the gut and the brain highlights the importance of a holistic approach to health, addressing both physical and mental well-being to optimize brain and gut health.

6 Ways to Improve Brain-Gut Health

  1. Follow a healthy diet: Eating a diet rich in fiber, whole grains, fruits, and vegetables can support a healthy gut microbiome. Fermented foods such as yogurt, kefir, sauerkraut, and kimchi can also be beneficial for gut health.

  2. Get regular exercise: Regular physical activity can help reduce stress and inflammation, which can improve gut health and cognitive function. Exercise has also been shown to improve gut microbiome diversity and function.

  3. Manage stress: Chronic stress can have a negative impact on gut health and cognitive function. Techniques such as mindfulness meditation, deep breathing, and yoga can help reduce stress and improve brain-gut health.

  4. Prioritize sleep: Getting enough restful sleep is crucial for overall health, including brain and gut health. Aim for 7-9 hours of sleep per night and establish a regular sleep schedule to support healthy circadian rhythms.

  5. Consider probiotics and prebiotics: Probiotic supplements can help improve gut microbiome diversity and function, while prebiotics (fibre-rich foods) can provide the necessary nutrients for beneficial gut bacteria to thrive.

  6. Minimize exposure to toxins: Toxins such as pesticides, heavy metals, and plastics can have a negative impact on gut health and cognitive function. Minimize exposure by choosing organic foods, filtering water, and avoiding plastic containers and food packaging.

Why checking and understanding the brain-gut connection with clients is crucial for massage therapists?

Checking the brain-gut connection with a client is a crucial component of massage therapy (especially in modalities with a specific abdomen sequence like Brazilian MLD) because it provides massage therapists with a deeper understanding of their client's overall health and well-being.

Understanding the brain-gut connection can significantly impact a client's experience during and after the massage.

By assessing the brain-gut connection, massage therapists can identify any gut-related issues that may affect the massage, such as bloating or abdominal discomfort, and adjust their massage techniques and pressure accordingly.

Furthermore, evaluating the brain-gut connection can offer valuable insights into the client's physical and mental health, allowing massage therapists to tailor the treatment and incorporate relaxation techniques for clients experiencing high levels of stress or anxiety, or those who have experienced trauma (past or present).

Establishing effective and caring communication with clients and thoroughly discovering their overall well-being is paramount during the consultation process, leading to a more personalized massage experience that fosters a deeper connection between the client and therapist.


The brain-gut connection is a complex and fascinating aspect of human health that has significant implications for both physical and mental well-being. Research has shown that the gut microbiome and the communication pathway between the gut and the brain play a crucial role in digestion, metabolism, immune function, mood regulation, and cognitive function.

To optimize brain-gut health, individuals can follow a healthy diet, get regular exercise, manage stress, prioritize sleep, consider probiotics and prebiotics, and minimize exposure to toxins. By prioritizing their brain-gut health, individuals can improve their overall health and well-being and potentially reduce their risk of a variety of health conditions.

In conclusion, whether you're looking to improve your digestion, support your immune system, enhance your cognitive function, or optimize your mental health, the brain-gut connection is a critical factor to consider. By taking steps to support this connection and prioritize your brain-gut health, you can unlock the full potential of your mind and body and live a healthier, happier life.


Interested in this topic and would like to dig deeper and learn more about it? Here are some resources, books and research papers about the brain-gut connection: these resources provide in-depth insights into the brain-gut connection, including the role of gut microbiome, stress, and neurochemicals in influencing brain and gut health.

  1. Mayer, E. A., Knight, R., Mazmanian, S. K., Cryan, J. F., & Tillisch, K. (2014). Gut microbes and the brain: paradigm shift in neuroscience. Journal of Neuroscience, 34(46), 15490-15496.

  2. Dinan, T. G., & Cryan, J. F. (2017). Gut-brain axis in 2016: brain-gut-microbiota axis-mood, metabolism and behaviour. Nature Reviews Gastroenterology & Hepatology, 14(2), 69-70.

  3. Foster, J. A., Rinaman, L., & Cryan, J. F. (2017). Stress & the gut-brain axis: Regulation by the microbiome. Neurobiology of Stress, 7, 124-136.

  4. "The Mind-Gut Connection: How the Hidden Conversation Within Our Bodies Impacts Our Mood, Our Choices, and Our Overall Health" by Emeran Mayer

  5. "Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life" by David Perlmutter

  6. "The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota" edited by Niall Hyland and Catherine Stanton

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